Topoisomerase I inhibitor 12
Selected Variant
HY-161082
Size: 1 Each
Topoisomerase I inhibitor 12 (compound 12), a Camptothecin -based derivative, is a potent Topoisomerase I inhibitor. Topoisomerase I inhibitor 12 shows anticancer activity[1].
Product Specifications
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-i-inhibitor-12.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C(N(CCN3CCOCC3)C(/C2=C\C4=CC=CC=C4)=O)=NC5=CC=CC=C51
Molecular Formula
C23H22N4O3
Molecular Weight
402.45
References & Citations
[1]Ahmed I. Khodair, et al. Camptothecin structure simplification elaborated new imidazo[2,1-b]quinazoline derivative as a human topoisomerase I inhibitor with efficacy against bone cancer cells and colon adenocarcinoma. European Journal of Medicinal Chemistry. 16 December 2023, 116049.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo I
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680883-100 1x 100 µL
PSA (Prostate Specific Antigen) (A67-B/E3), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741815-500 1x 500 µL
Chromogranin A / CHGA (Neuroendocrine Marker) (CHGA/1815R), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741071-500 1x 500 µL
Ksp-Cadherin / CDH16 (CDH16/1071), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880678-500 1x 500 µL
Involucrin (SY5), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details