4'-Ethynyl-2'-deoxycytidine

4'-Ethynyl-2'-deoxycytidine is an anticancer nucleoside. 4'-Ethynyl-2'-deoxycytidine can used in study acute lymphoblastic leukemia and diffuse large B-cell lymphoma[1].

Product Specifications

CAS Number

[232588-95-3]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4-ethynyl-2-deoxycytidine.html

Solubility

10 mM in DMSO

Smiles

N=C1N=C(O)N([C@@H]2O[C@@](CO)(C#C)[C@@H](O)C2)C=C1

Molecular Formula

C11H13N3O4

Molecular Weight

251.24

References & Citations

[1]Calbert ML, et al. 4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress. Mol Cancer Ther. 2023 Dec 8.