QP5020
QP5020 (compound 28) is an inhibitor of QPCTL with an IC50 value of 15 nM. QP5020 has antitumor efficacy[1].
Product Specifications
CAS Number
3027434-06-3
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/qp5020.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=CC(C2=CC=C(F)N=C2)=C1N3CCC(C4=NN=CN4C)CC3
Molecular Formula
C20H19FN6
Molecular Weight
362.40
References & Citations
[1]Lei Yu, et al. Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy. Signal Transduct Target Ther. 2023, 8, 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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