KTt-45
KTt-45 is a T-type calcium channel blocker. KTt-45 has anticancer effect by inducing apoptosis on HeLa cervical cancer cell line[1].
Product Specifications
CAS Number
2244987-60-6
UNSPSC
12352005
Target
Apoptosis; Calcium Channel; Caspase
Type
Reference compound
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ktt-45.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C/C=C(CC)/CC)C(O)=C(C(CC(C2=CC=CC=C2O)O3)=O)C3=C1
Molecular Formula
C22H24O5
Molecular Weight
368.42
References & Citations
[1]Du N H, et al. KTt-45, a T-type calcium channel blocker, acts as an anticancer agent by inducing apoptosis on HeLa cervical cancer cell line [J]. Scientific Reports, 2023, 13 (1) : 22092.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 3; Caspase 9; T-type calcium channel
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