hACE2/SP-IN-1
Product Specifications
UNSPSC Description
hACE2/SP-IN-1 (compound 7a) is a dual inhibitor of hACE2 and coronavirus spike protein. hACE2/SP-IN-1 can bind to the spike protein and block cell entry, preventing SARS-CoV-2 from infecting human cells[1].
Target Antigen
Angiotensin-converting Enzyme (ACE); SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hace2-sp-in-1.html
Solubility
10 mM in DMSO
Smiles
O=[N+]([O-])C(C=C1)=CC=C1/C=N/C2=C(C3=CC=CC=C3)N=C4N2C=CC=N4
Molecular Weight
343.34
References & Citations
[1]Azzouzi M, et al. Design, synthesis, and computational studies of novel imidazo[1,2-a]pyrimidine derivatives as potential dual inhibitors of hACE2 and spike protein for blocking SARS-CoV-2 cell entry. J Mol Struct. 2023 Aug 5;1285:135525.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161068/hACE2-SP-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161068/
Clinical Information
No Development Reported
Curated Selection
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