Arginase inhibitor 7
Arginase inhibitor 7 (compound A17) is an arginase (ARG1) inhibitor, with an IC50 of 0.16 μM. Arginase inhibitor 7 has high oral bioavailability[1].
Product Specifications
CAS Number
2377392-07-7
UNSPSC
12352005
Target
Arginase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arginase-inhibitor-7.html
Solubility
10 mM in DMSO
Smiles
NC(NCCC[C@@H](C(N1C[C@@H](CCB(O)O)C[C@](N)(C(O)=O)C1)=O)N)=N
Molecular Formula
C14H29BN6O5
Molecular Weight
372.23
References & Citations
[1]Gzik A, et al. Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion. Eur J Med Chem. 2023 Dec 10;264:116033.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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