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ECDD-S16

ECDD-S16 is a potent inhibitor of pyroptosis. ECDD-S16 inhibits surface and endosomal TLR ligands activated pyroptosis in Raw264.7 cells[1].

Product Specifications

UNSPSC

12352005

Target

Pyroptosis

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ecdd-s16.html

Solubility

10 mM in DMSO

Smiles

FC1=CC=C(C(O[C@H]2[C@H](OC3=C(COC4=O)C4=C(C5=CC=C6C(OCO6)=C5)C7=CC(OC)=C(OC)C=C73)OC[C@@H](OC)[C@@H]2OC)=O)C=C1

Molecular Formula

C35H31FO12

Molecular Weight

662.61

References & Citations

[1]Ekchariyawat P, et al. ECDD-S16 targets vacuolar ATPase: A potential inhibitor compound for pyroptosis-induced inflammation. PLoS One. 2023 Nov 27;18 (11) :e0292340.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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