ECDD-S16
ECDD-S16 is a potent inhibitor of pyroptosis. ECDD-S16 inhibits surface and endosomal TLR ligands activated pyroptosis in Raw264.7 cells[1].
Product Specifications
UNSPSC
12352005
Target
Pyroptosis
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ecdd-s16.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C(O[C@H]2[C@H](OC3=C(COC4=O)C4=C(C5=CC=C6C(OCO6)=C5)C7=CC(OC)=C(OC)C=C73)OC[C@@H](OC)[C@@H]2OC)=O)C=C1
Molecular Formula
C35H31FO12
Molecular Weight
662.61
References & Citations
[1]Ekchariyawat P, et al. ECDD-S16 targets vacuolar ATPase: A potential inhibitor compound for pyroptosis-induced inflammation. PLoS One. 2023 Nov 27;18 (11) :e0292340.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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