MDM2-p53-IN-19
MDM2-p53-IN-19 (Compound A-8d) is a chemical intermediate that can be used to synthesize inhibitors of the MDM2-p53 interaction with anticancer activity[1].
Product Specifications
CAS Number
1818292-01-1
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdm2-p53-in-19.html
Solubility
10 mM in DMSO
Smiles
OCC[C@H]1[C@@H]([N+]([O-])=O)[C@H](C2=C(C(Cl)=CC=C2)F)[C@@]3(C4=CC=C(Cl)C=C4NC3=O)N1CC5CC5
Molecular Formula
C23H22Cl2FN3O4
Molecular Weight
494.34
References & Citations
[1]Andreas Gollner, et al. Spiro[3h-indole-3,2'-pyrrolidin]-2 (1h) -one derivatives and their use as mdm2-p53 inhibitors. Patent WO2015155332A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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