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MDM2-p53-IN-18

MDM2-p53-IN-18 (Compd A-7b) is a MDM2-p53 interaction inhibitor[1].

Product Specifications

CAS Number

[1818291-95-0]

UNSPSC

12352005

Target

MDM-2/p53

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mdm2-p53-in-18.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@@]2(C3=CC=C(Cl)C=C3N1)[C@@H](C4=C(C(Cl)=CC=C4)F)[C@@H]([C@@H](N2)CCO)[N+]([O-])=O

Molecular Formula

C19H16Cl2FN3O4

Molecular Weight

440.25

References & Citations

[1]GOLLNER, et al. SPIRO[3H-INDOLE-3,2'-PYRROLIDIN]-2 (1H) -ONE DERIVATIVES AND THEIR USE AS MDM2-P53 INHIBITORS. Patent. WO2015155332A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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