JM-9
JM-9 is a inhibitor of MD2. JM-9 suppresses high glucose and palmitic acid -induced inflammation in MPMs. JM-9 improves diabetic kidney disease by inhibiting MD2-mediated inflammation[1].
Product Specifications
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jm-9.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)C1=C(/C=C2CCCC(/C\2=N\O)=C\C3=CC=CC=C3C(F)(F)F)C=CC=C1
Molecular Formula
C22H17F6NO
Molecular Weight
425.37
References & Citations
[1]Wang M, et al. Inhibition of MD2 by natural product-drived JM-9 attenuates renal inflammation and diabetic nephropathy in mice. Biomed Pharmacother. 2023 Dec;168:115660.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15304201 1 Vial
Lentiviral mouse Klk1b5 shRNA (UAS) - Lentiviral mouse Klk1b5 shRNA (UAS, GFP) plasmid
Sign In for Pricing
View Details 035792 200 µL
FUNDC1, NT (FUNDC1, FUN14 domain-containing protein 1)
Sign In for Pricing
View Details MBS1063719-01 0.02 mg (E-Coli)
Recombinant Chlorella vulgaris Putative cell division topological specificity factor (minE)
Sign In for Pricing
View Details