AC2 selective-IN-1
AC2 selective-IN-1 (compound 14) is a potent (IC50=4.45 μM), non-toxic, and selective mAC2 inhibitor[1].
Product Specifications
UNSPSC
12352005
Target
Adenylate Cyclase
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac2-selective-in-1.html
Solubility
10 mM in DMSO
Smiles
NC1=C2C(N(CCOCP(N[C@H](C(OC(C)C)=O)CC3=CC=CC=C3)(N[C@@H](CC4=CC=CC=C4)C(OC(C)C)=O)=O)C=C2C5=CC=CC(C(N6)=NOC6=O)=C5)=NC=N1
Molecular Formula
C41H47N8O8P
Molecular Weight
810.83
References & Citations
[1]Pavel Kraina, et al. Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir. Bioorg Med Chem. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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