ARQ-736
ARQ-736 is a potent and selective B-RAF inhibitor that plays an important role in cancer study[1].
Product Specifications
CAS Number
[1228237-57-7]
UNSPSC
12352005
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arq-736.html
Solubility
10 mM in DMSO
Smiles
O=P(O[Na])(O[Na])OCOC1=CC=CC(C(N=C2N3C=CO2)=C3C4=NC(N[C@H]5CN(CCC5)S(=O)(C6=NN(C)C=C6)=O)=NC=C4)=C1
Molecular Formula
C25H25N8Na2O8PS
Molecular Weight
674.53
References & Citations
[1]Tiangui Huang, et al. B-Raf and the inhibitors: from bench to bedside. J Hematol Oncol. 2013 Apr 25:6:30.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16063/ARQ-736-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16063/
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
B-Raf
Curated Selection
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