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Arbutamine (hydrochloride)

Arbutamine hydrochloride is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine hydrochloride stimulates cardiac β1-, tracheal β2-, and adiopocyte β3- adrenergic receptors. Arbutamine hydrochloride provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine hydrochloride can be used for cardiac stress agent [1][2][3].

Product Specifications

CAS Number

125251-66-3

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/arbutamine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C([C@@H](O)CNCCCCC2=CC=C(O)C=C2)C=C1O.[H]Cl

Molecular Formula

C18H24ClNO4

Molecular Weight

353.84

References & Citations

[1]Ruiz M, et al. Arbutamine stress perfusion imaging in dogs with critical coronary artery stenoses: (99m) Tc-sestamibi versus (201) Tl. J Nucl Med. 2002 May;43 (5) :664-70.|[2]Nagarajan R, et al. A novel catecholamine, arbutamine, for a pharmacological cardiac stress agent. Cardiovasc Drugs Ther. 1996 Mar;10 (1) :31-8.|[3]Abou-Mohamed G, et, al. Characterization of the adrenergic activity of arbutamine, a novel agent for pharmacological stress testing. Cardiovasc Drugs Ther. 1996 Mar;10 (1) :39-47.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β adrenergic receptor

Frequently Asked Questions

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