P53 Activator 11
P53 Activator 11 (compound A-1) is a potent p53 activator with an EC50 value of 0.478 µM for p53 (Y220C) . p53 Activator 11 has the potential for the research of cancer[1].
Product Specifications
CAS Number
2850211-42-4
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-activator-11.html
Solubility
10 mM in DMSO
Smiles
O=S(N)(C1=CC=C(NCC#CC2=C(N3C=CC=C3)N4C=CC=C(NC5CCN(CC5)C)C4=N2)C=C1)=O
Molecular Formula
C26H29N7O2S
Molecular Weight
503.62
References & Citations
[1]Sujing LI, et al. Compounds targeting y220c mutant of p53. WO2022213975A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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