P53 Activator 9
P53 Activator 9 (example D-4) is a p53 activator with EC50 of 1.699μM[1].
Product Specifications
CAS Number
[2849345-37-3]
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-activator-9.html
Solubility
10 mM in DMSO
Smiles
CC(NC1CCN(C)CC1)C2=CC3=C(N4C(C#CCNC5=CC=C(S(N)(=O)=O)C=C5)=C3)C(SCCC4)=C2
Molecular Formula
C28H35N5O2S2
Molecular Weight
537.74
References & Citations
[1]Sujing LI, et al. Compounds targeting y220c mutant of p53. Patent WO2022213975A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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