TNF-α-IN-14
TNF-α-IN-14 is a potent and selective TNFα inhibitor with an IC50 value of 1.1 µM. TNF-α-IN-14 shows antiinflammatory properties (WO2001072735A2; compound 12) [1].
Product Specifications
CAS Number
364039-54-3
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tnf-α-in-14.html
Solubility
10 mM in DMSO
Smiles
CCOCC1=CC(C=CC(OC)=C2)=C2OC1C3=CC(OC)=C(C(OC)=C3)OC
Molecular Formula
C22H26O6
Molecular Weight
386.44
References & Citations
[1]Jie Fei Cheng, et al. Benzopyranes useful as tnf alpha inhibitors. WO2001072735A2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TNFRSF5/CD40
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