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TNF-α-IN-14

TNF-α-IN-14 is a potent and selective TNFα inhibitor with an IC50 value of 1.1 µM. TNF-α-IN-14 shows antiinflammatory properties (WO2001072735A2; compound 12) [1].

Product Specifications

CAS Number

364039-54-3

UNSPSC

12352005

Target

TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tnf-α-in-14.html

Solubility

10 mM in DMSO

Smiles

CCOCC1=CC(C=CC(OC)=C2)=C2OC1C3=CC(OC)=C(C(OC)=C3)OC

Molecular Formula

C22H26O6

Molecular Weight

386.44

References & Citations

[1]Jie Fei Cheng, et al. Benzopyranes useful as tnf alpha inhibitors. WO2001072735A2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

TNFRSF5/CD40

Frequently Asked Questions

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