TNF-α-IN-12
TNF-α-IN-12 is a TNF-α inhibitor with IC50 of 0.1 μM. TNF-α-IN-12 can decrease the TNF-α blood levels[1].
Product Specifications
CAS Number
[364039-56-5]
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tnf-α-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C(C)C1=CC2=C(OC1C3=CC(OC)=C(C(OC)=C3)OC)C=C(OC)C=C2
Molecular Formula
C21H22O6
Molecular Weight
370.40
References & Citations
[1]Jie Fei Cheng, et al. Benzopyranes useful as tnf alpha inhibitors. Patent WO2001072735A2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TNFRSF5/CD40
Curated Selection
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