Akt1-IN-2
AKT-I-1 is a selective inhibitor of Akt1, with an IC50 of 4.6 µM[1].
Product Specifications
CAS Number
[473382-39-7]
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/akt1-in-2.html
Solubility
10 mM in DMSO
Smiles
CC(CNC1=NN2C(C=C1C3CCC3)=NN=C2C4=CC=CC=C4)(C)CN(C)C
Molecular Formula
C22H30N6
Molecular Weight
378.51
References & Citations
[1]Barnett SF, et al. Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors. Biochem J. 2005 Jan 15;385 (Pt 2) :399-408.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Akt1; Akt2; Akt3
Available Sizes
Curated Selection
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