CCD-2
CCD-2 is a conventional detergent and is readily degraded. CCD-2 can efficiently solubilize and stabilize diverse G protein-coupled receptors (GPCRs) . CCD-2 is amenable to the β-barrel protein research. The chemical cleavage of CCD-2 is rapid, complete and biorthogonal and should facilitate a chemical methodology for in situ detergent replacement in diverse membrane proteins (MPs) studies[1].
Product Specifications
CAS Number
2271351-19-8
UNSPSC
12352005
Target
Adenosine Receptor; GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ccd-2.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H](O[C@H]([C@@H]([C@H]1O)O)SSCCCCCCCCCC)[C@H]1O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO
Molecular Formula
C22H42O10S2
Molecular Weight
530.69
References & Citations
[1]Dongxiang Xue, et al. A Chemical Strategy for Amphiphile Replacement in Membrane Protein Research. Langmuir. 2019 Mar 26;35 (12) :4319-4327.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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