THR-β agonist 7
THR-β agonist-1 (Example 2) is a THR-β agonist, with EC50 values of 52 nM and 1017 nM for THR-β and THR-α, respectively[1].
Product Specifications
CAS Number
2604229-32-3
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CC(Br)=C(C(Cl)=C2)OC(C=C3C(C([2H])([2H])[2H])C([2H])([2H])[2H])=NNC3=O)N=C(C(N1)=O)C#N
Molecular Formula
C17H6D6BrClN6O4
Molecular Weight
485.71
References & Citations
[1], et al. Halogen-substituted phenylate compound and applications thereof. Patent WO2021032161A1.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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