PROTAC ER Degrader-12
PROTAC ER Degrader-12 (Compound 70) is an estrogen receptor PROTAC degrader (DC50: 50: [1].
Product Specifications
UNSPSC
12352005
Target
Estrogen Receptor/ERR; PROTACs
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/er-degrader-8.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C1CCC(NC1=O)=O)C2)C3=C2C=C(C=C3)N(C4)CC4(CC5)CCN5CC(CC6)CCN6C7=CC=C([C@@H]8C(C=CC(O)=C9)=C9OC[C@@H]8C%10=C(F)C=CC=C%10F)C=C7F
Molecular Formula
C47H48F3N5O5
Molecular Weight
819.91
References & Citations
[1], et al. Aromatic compound, method for preparing same, and use thereof in preparation of estrogen receptor degrader. Patent WO2023241598A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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