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AR/BET protein degrader-1

Product Specifications

UNSPSC Description

AR/BET protein degrader-1 (Compound 149) is an Androgen Receptor and BET (bromodomain and extra-terminal domain) protein degrader that can be used in cancer research[1].

Target Antigen

Androgen Receptor; Epigenetic Reader Domain; PROTACs

Type

Reference compound

Related Pathways

Epigenetics;PROTAC;Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ar-bet-protein-degrader-1.html

Solubility

10 mM in DMSO

Smiles

CC1=NOC(C)=C1C2=CC=C(C)C(N(C[C@@H]3CC[C@@H](CNC4=CC(C(N(C5CCC(NC5=O)=O)C6=O)=O)=C6C=C4)CC3)C7=CC=C(C8(C#N)CC8)C=C7)=C2

Molecular Weight

724.85

References & Citations

[1]Lyu Haibin, et al. Aromatic Amine Ar and Bet Targeted Protein Degradation Chimeric Compound and Application Thereof. CN-111944012-A

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-160262/AR-BET-protein-degrader-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-160262/

Clinical Information

No Development Reported

CAS Number

2571123-81-2

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