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GDP-Fucose-Tz

GDP-Fucose-Tz (GDP-Fucose-Am-Tz) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. GDP-fucose-Am-Tz and TCO-ssDNA were reacted at a ratio of 1:1 to obtain the final product GDP-fucose-ssDNA[1].

Product Specifications

CAS Number

2762518-76-1

Product Name Alternative

GDP-Fucose-Am-Tz

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/gdp-fucose-tz.html

Solubility

10 mM in DMSO

Smiles

O=C1NC(N)=NC2=C1N=CN2[C@@H]3O[C@H](COP(OP(O[C@H]4O[C@@H](CNC(CCOCCOCCOCCOCCOC5=CC=C(C6=NN=C(C)N=N6)C=C5)=O)[C@@H](O)[C@@H](O)[C@@H]4O)(O)=O)(O)=O)[C@@H](O)[C@H]3O

Molecular Formula

C36H52N10O21P2

Molecular Weight

1022.80

References & Citations

[1]Yu W, et al. Chemoenzymatic Measurement of LacNAc in Single-Cell Multiomics Reveals It as a Cell-Surface Indicator of Glycolytic Activity of CD8+ T Cells. J Am Chem Soc. 2023 Jun 14;145 (23) :12701-12716.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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