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ORN 02

ORN 02 is a synthetic single-stranded U-rich RNA and contains 6 repeats of UUAU sequence motif. The AU-rich oligoribonucleotides (ORNs) are able to stimulate TLR8[1].

Product Specifications

CAS Number

[937769-72-7]

UNSPSC

12352208

Target

Toll-like Receptor (TLR)

Type

Oligonucleotides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/orn-02.html

Solubility

10 mM in DMSO|10 mM in H2O

Smiles

[ORN02]

References & Citations

[1]Alexandra Forsbach, et al. Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses. J Immunol. 2008 Mar 15;180 (6) :3729-38.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Isoform

TLR8

Curated Selection

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