HSV-60mer (sodium)

HSV-60mer sodium is a 60 bp double-stranded oligonucleotide containing viral DNA motifs that derive from the herpes simplex virus 1 (HSV-1) genome[1]. Transfected HSV-60 has been shown to potently induce IFN-β in a Toll-like receptor (TLR) -, DNA-dependent activator of IRFs (DAI) -, and RNA polymerase III (Pol III) -independent, but STING-, TBK1- and IFN regulatory factor 3 (IRF3) -dependent manner.