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KRAS inhibitor-23

KRAS inhibitor-23 (Isomer 2 of compound i) is a potent inhibitor of KRAS that plays an important role in cancer research[1].

Product Specifications

CAS Number

2641747-55-7

UNSPSC

12352005

Target

Ras

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(N3[C@H](CN(CC3)C(C=C)=O)C(N2C([2H])([2H])[2H])=O)C4=CC(Cl)=C(C5=C(C=CC=C5O)F)N=C4N1C6=C(N=CC=C6C)C(C)C

Molecular Formula

C32H27D3ClFN6O4

Molecular Weight

620.09

References & Citations

[1]GenFleet Therapeutics (Shanghai) Inc., et al. Salt or polymorph of KRAS inhibitor. World Intellectual Property Organization, WO2022223037 A1 2022-10-27

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

K-Ras

Frequently Asked Questions

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