HPK1-IN-42
HPK1-IN-42 (compound 185) ia a HPK1 inhibitor with the IC50 50 of 0.24 nM[1].
Product Specifications
CAS Number
2848684-50-2
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-42.html
Solubility
10 mM in DMSO
Smiles
CN(N=C1)C(C)=C1C2=C(CN3)C(C3=NC=C4C5=NC(CN(C)C)=C(C6CCOCC6)S5)=C4C=C2
Molecular Formula
C26H30N6OS
Molecular Weight
474.62
References & Citations
[1]Zhou fusheng, et al. Spiro-substituted pyrimidine-fused cyclic compound, preparation method therefor and medical use thereof. WO2022214044A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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