HPK1-IN-41
HPK1-IN-41 (compound Z389) is a HPK1 inhibitor with an IC50 value of 0.21 μM. HPK1-IN-41 can be used for the research of preventing and/or treating diseases or conditions associated with HPK1 activity[1].
Product Specifications
CAS Number
[2828455-23-6]
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-41.html
Solubility
10 mM in DMSO
Smiles
CC1=CNC2=C1C=C(C3=CC(CCN(C(N4CC5OC(CC5)C4)=O)C6)=C6C([C@@H]7CCCN7)=C3)C=N2
Molecular Formula
C28H33N5O2
Molecular Weight
471.59
References & Citations
[1]ZHOU fusheng, et al. Fused ring substituted six-membered heterocyclic compound, preparation method therefor and use thereof. WO2022184152A1. 2023.|[2], . . . WO2022184152A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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