HPK1-IN-41

HPK1-IN-41 (compound Z389) is a HPK1 inhibitor with an IC50 value of 0.21 μM. HPK1-IN-41 can be used for the research of preventing and/or treating diseases or conditions associated with HPK1 activity[1].

Product Specifications

CAS Number

[2828455-23-6]

UNSPSC

12352005

Target

MAP4K

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hpk1-in-41.html

Solubility

10 mM in DMSO

Smiles

CC1=CNC2=C1C=C(C3=CC(CCN(C(N4CC5OC(CC5)C4)=O)C6)=C6C([C@@H]7CCCN7)=C3)C=N2

Molecular Formula

C28H33N5O2

Molecular Weight

471.59

References & Citations

[1]ZHOU fusheng, et al. Fused ring substituted six-membered heterocyclic compound, preparation method therefor and use thereof. WO2022184152A1. 2023.|[2], . . . WO2022184152A1.