JA397
JA397, a chemical probe, is a potent and selective inhibitor for the TAIRE family with cellular activity ranging from IC50 values of 21 nM to 307 nM[1].
Product Specifications
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ja397.html
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)NC(C=C1)=CC=C1CNC2=NC=CC(NC3=NNC(C(OC(C)(C)C)=O)=C3)=N2
Molecular Formula
C24H31N7O4
Molecular Weight
481.55
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK14; CDK16
Curated Selection
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