KIO-301
KIO-301 is a photoswitchable HCN channel blocker, and can be used as the vitreous “light switch” molecule that reactivates retinitis pigmentosa[1].
Product Specifications
CAS Number
[1643463-61-9]
UNSPSC
12352005
Target
HCN Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/kio-301.html
Solubility
10 mM in DMSO
Smiles
O=C(C[N+](CC)(CC)CC)NC1=CC=C(C=C1)/N=N/C2=CC=C(N(CC)CC3=CC=CC=C3)C=C2.[Br-]
Molecular Formula
C29H38BrN5O
Molecular Weight
552.55
References & Citations
[1]drughunter.com. Small Molecules of the Month. November 2023
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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