BI-8668
BI-8668 (compound 40), a chemical probe, is an inhibitor of ENaC. BI-8668 can be used in the study of cystic fibrosis[1].
Product Specifications
CAS Number
[2084059-97-0]
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bi-8668.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC(Cl)=CN=C1N)NCC2=[N+](CC)C3=C(C=CC(C(N(CCN(C)C)C)=O)=C3)N2CC.[Cl-]
Molecular Formula
C23H32Cl2N8O2
Molecular Weight
523.46
References & Citations
[1]Betzemeier B, et al. Discovery and development of BI 1265162, an ENaC inhibitor for the treatment of cystic fibrosis. Eur J Med Chem. 2023 Dec 18;265:116038.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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