BCR-ABL kinase-IN-3 (dihydrocholide)
BCR-ABL kinase-IN-3 (dihydrocholide) (example 1) is a potent inhibitor of BCR-ABL that plays an important role in acute myeloid leukemia (AML) research[1].
Product Specifications
UNSPSC
12352005
Target
Bcr-Abl
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcr-abl-kinase-in-3-dihydrocholide.html
Solubility
10 mM in DMSO
Smiles
CN(N=C1)C=C1NC2=CC=CN3C2=NC=C3C#CC4=C(C)C=C(F)C(C(NC5=CC(N6C=C(C)N=C6)=CC(C(C#N)(C)C)=C5)=O)=C4.[H]Cl.[H]Cl
Molecular Formula
C35H32Cl2FN9O
Molecular Weight
684.59
References & Citations
[1]Lee Doohyun, et al. Preparation of 3- ((8- ((1H-pyrazol-4-yl) amino) imidazo[1,2-a]pyridin-3-yl) ethynyl) -N-phenylbenzamide derivatives for prevention or treatment of cancer. World Intellectual Property Organization, WO2021172931 A1 2021-09-02
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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