Necrosis inhibitor 3
Necrosis inhibitor 3 (compound B3) is a poteng inhibitor of necrosis, with the IC50 value of 0.29 nM in HT29 cells[1].
Product Specifications
CAS Number
2258670-86-7
UNSPSC
12352005
Target
Necroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/necrosis-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=C(OCC1)N=CC(C3=CC4=C(N=C(NC(C5CC5)=O)S4)C=C3)=C2)OC6CCCCC6
Molecular Formula
C25H26N4O4S
Molecular Weight
478.56
References & Citations
[1]Zhang Xiaohu, et al. Preparation of heteroaryl compounds as inhibitors of necrosis, composition and method using the same. World Intellectual Property Organization, WO2018237370 A1 2018-12-27
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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