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Necrosis inhibitor 2 (hydrocholide)

Necrosis inhibitor 2 hydrocholide (Compound B19) is a cell necrosis inhibitor. Necrosis inhibitor 2 hydrocholide can be used to study diseases related to the necrosis pathway, including inflammation, tumors, metabolic diseases and neurodegenerative diseases[1].

Product Specifications

UNSPSC

12352005

Target

Necroptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/necrosis-inhibitor-2-hydrocholide.html

Solubility

10 mM in DMSO

Smiles

O=C(N1C2=C(OCC1)N=CC(C3=CN4C=C(NC(C5CC5)=O)N=C4C=C3)=C2)OC6CCOCC6.[H]Cl

Molecular Formula

C24H26ClN5O5

Molecular Weight

499.95

References & Citations

[1]Xiaohu Zhang, et al. Heteroaryl compounds as inhibitors of necrosis, composition and method using the same. Patent WO2018237370A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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