Necrosis inhibitor 2 (hydrocholide)
Necrosis inhibitor 2 hydrocholide (Compound B19) is a cell necrosis inhibitor. Necrosis inhibitor 2 hydrocholide can be used to study diseases related to the necrosis pathway, including inflammation, tumors, metabolic diseases and neurodegenerative diseases[1].
Product Specifications
UNSPSC
12352005
Target
Necroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/necrosis-inhibitor-2-hydrocholide.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=C(OCC1)N=CC(C3=CN4C=C(NC(C5CC5)=O)N=C4C=C3)=C2)OC6CCOCC6.[H]Cl
Molecular Formula
C24H26ClN5O5
Molecular Weight
499.95
References & Citations
[1]Xiaohu Zhang, et al. Heteroaryl compounds as inhibitors of necrosis, composition and method using the same. Patent WO2018237370A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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