2-2 (t) aptamer (sodium)
2-2 (t) aptamer sodium is a 42-nucleotide trimeric complex of aptamer (2-2) targeting ErbB-2. 2-2 (t) aptamer sodium inhibits the growth of gastric cancer cells in vitro and in vivo[1].
Product Specifications
UNSPSC
12352208
Target
EGFR
Type
Oligonucleotides
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-2-t-aptamer-sodium.html
Solubility
10 mM in DMSO
Smiles
[2-2(t)aptamer(sodium)]
References & Citations
[1]Mahlknecht G, Maron R, Mancini M, Schechter B, Sela M, Yarden Y. Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth. Proc Natl Acad Sci U S A. 2013 May 14;110 (20) :8170-5.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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