SW1 aptamer (sodium)

SW1 aptamer sodium is a high-affinity DNA aptamer (Kd: 123.62 nM) that targets liver cancer SMMC-7721 cells and targets intracellular components within the nucleus. SW1 aptamer sodium can also identify various other types of cancer cells and tissues, serving as an effective molecular probe for clinical cancer diagnosis[1].

Product Specifications

UNSPSC

12352208

Target

DNA Alkylator/Crosslinker; Fluorescent Dye

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sw1-aptamer-sodium.html

Solubility

10 mM in DMSO

Smiles

[SW1aptamer(sodium)]

References & Citations

[1]Li L, Wan J, Wen X, Guo Q, Jiang H, Wang J, Ren Y, Wang K. Identification of a New DNA Aptamer by Tissue-SELEX for Cancer Recognition and Imaging. Anal Chem. 2021 May 18;93 (19) :7369-7377.