P12FR2 aptamer (sodium)
Product Specifications
UNSPSC Description
P12FR2 aptamer sodium is a 2'-fluoropyrimidine-modified RNA aptamer targeting human PAUF with an estimated apparent KD of 77 nM. P12FR2 aptamer sodium inhibits PAUF-induced migration of PANC-1 (human pancreatic cancer cells) in wound healing assays and suppresses tumor growth in a mouse CFPAC-1 pancreatic cancer model[1].
Target Antigen
Biochemical Assay Reagents
Type
Oligonucleotides
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/p12fr2-aptamer-sodium.html
Solubility
10 mM in DMSO
Smiles
[P12FR2 aptamer (sodium)]
References & Citations
[1]Kim YH, Sung HJ, Kim S, Kim EO, Lee JW, Moon JY, Choi K, Jung JE, Lee Y, Koh SS, Rhee SG, Heo K, Kim IH. An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells. Cancer Lett. 2011 Dec 26;313(1):76-83.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160061/P12FR2-aptamer-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160061/
Clinical Information
No Development Reported
Curated Selection
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