Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

AP1153 aptamer (sodium)

AP1153 aptamer sodium is a DNA aptamer that specifically binds to the cholecystokinin receptor CCKBR (Kd: ~15 pM), but does not activate CCKBR-related signaling pathways. AP1153 aptamer sodium is internalized by pancreatic ductal adenocarcinoma (PDAC) cells in a receptor-mediated manner. AP1153 aptamer sodium can bioconjugate to the surface of fluorescent nanoparticles to facilitate nanoparticle delivery to PDAC tumors in vivo[1].

Product Specifications

UNSPSC

12352208

Target

Cholecystokinin Receptor

Type

Oligonucleotides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ap1153-aptamer-sodium.html

Solubility

10 mM in DMSO

Smiles

[AP1153aptamer(sodium)]

References & Citations

[1]Clawson GA, Abraham T, Pan W, Tang X, Linton SS, McGovern CO, Loc WS, Smith JP, Butler PJ, Kester M, Adair JH, Matters GL. A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma. Nucleic Acid Ther. 2017 Feb;27 (1) :23-35.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

3-Pentanol
TRC-P227295-50ML 50 mL

3-Pentanol

Sign In for Pricing
View Details
Pentafluorobenzoic Acid
TRC-P273515-5G 5 g

Pentafluorobenzoic Acid

Sign In for Pricing
View Details
Vmn1r81 Mouse Gene Knockout Kit (CRISPR)
KN519098 1 Kit

Vmn1r81 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
CMG1 (IFT74) Rabbit Polyclonal Antibody
TA377362 100 µL

CMG1 (IFT74) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Tropomyosin 2 (TPM2) (NM_213674) Human Recombinant Protein
TP304007 20 µg

Tropomyosin 2 (TPM2) (NM_213674) Human Recombinant Protein

Sign In for Pricing
View Details
CD14 Polyclonal Antibody
E-AB-70113-01 60 µL

CD14 Polyclonal Antibody

Sign In for Pricing
View Details