PRMT5-IN-32
PRMT5-IN-32 is an inhibitor of PRMT5. PRMT5-IN-32 inhibits HCT116 cell proliferation with an IC 50 of 0.13 μM[1].
Product Specifications
CAS Number
2918815-34-4
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt5-in-32.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC(F)=CC=C2[C@@]3(C(N(CC3)CC4=C(C=C(C(F)=C4)F)F)=O)N1CC5=CC6=C(C)C=C(N)N=C6N5
Molecular Formula
C27H21F4N5O2
Molecular Weight
523.48
References & Citations
[1]James Michael Smith, et al. Spirocyclic compounds. United States, US20230357279A1. 2023-11-09.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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