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PRMT5-IN-32

PRMT5-IN-32 is an inhibitor of PRMT5. PRMT5-IN-32 inhibits HCT116 cell proliferation with an IC 50 of 0.13 μM[1].

Product Specifications

CAS Number

2918815-34-4

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/prmt5-in-32.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=CC(F)=CC=C2[C@@]3(C(N(CC3)CC4=C(C=C(C(F)=C4)F)F)=O)N1CC5=CC6=C(C)C=C(N)N=C6N5

Molecular Formula

C27H21F4N5O2

Molecular Weight

523.48

References & Citations

[1]James Michael Smith, et al. Spirocyclic compounds. United States, US20230357279A1. 2023-11-09.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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