IDO antagonist-1
Product Specifications
UNSPSC Description
IDO antagonist-1 (compound 163) is an antagonist of IDO . IDO antagonist-1 inhibits pancreatic adenocarcinoma cells growth in C57BL/6 mice[1].
Target Antigen
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido-antagonist-1.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H](NC(C1=CC=CC=C1OCC2=CN3N=N2)=O)CC(C)C)N(CCC4)[C@@]4([H])C(N([C@H](C(NCCCCCCCC3)=O)CC5=CC=CC=C5)C)=O
Molecular Weight
699.88
References & Citations
[1]Timothy F. Briggs, et al. Macrocyclic compounds for the inhibition of indoleamine-2,3-dioxygenase activity and use thereof. WO2018053302A1. 2018-03-22.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160025/IDO-antagonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160025/
Clinical Information
No Development Reported
CAS Number
2206797-88-6
Curated Selection
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