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IDO antagonist-1

Product Specifications

UNSPSC Description

IDO antagonist-1 (compound 163) is an antagonist of IDO . IDO antagonist-1 inhibits pancreatic adenocarcinoma cells growth in C57BL/6 mice[1].

Target Antigen

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ido-antagonist-1.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H](NC(C1=CC=CC=C1OCC2=CN3N=N2)=O)CC(C)C)N(CCC4)[C@@]4([H])C(N([C@H](C(NCCCCCCCC3)=O)CC5=CC=CC=C5)C)=O

Molecular Weight

699.88

References & Citations

[1]Timothy F. Briggs, et al. Macrocyclic compounds for the inhibition of indoleamine-2,3-dioxygenase activity and use thereof. WO2018053302A1. 2018-03-22.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-160025/IDO-antagonist-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-160025/

Clinical Information

No Development Reported

CAS Number

2206797-88-6

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