ET516
ET516 is a potent inhibitor of Androgen Receptor. ET516 significantly inhibits the proliferation and tumor growth of prostate cancer cells expressing AR-resistant mutants[1].
Product Specifications
CAS Number
2820120-95-2
UNSPSC
12352005
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/et516.html
Purity
99.13
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC1=CC(C(C)(C)C2=CC=C(C=C2)C#CC3=CN=C(NS(=O)(C)=O)N=C3)=CC(Cl)=C1OCCCl
Molecular Formula
C25H22Cl2N4O3S
Molecular Weight
529.44
References & Citations
[1]Xie J, et al. Targeting androgen receptor phase separation to overcome antiandrogen resistance. Nat Chem Biol. 2022 Dec;18 (12) :1341-1350.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Uncoated Human CGβ (Chorionic Gonadotrophin Beta) ELISA Kit
Uncoated Human CGβ (Chorionic Gonadotrophin Beta) ELISA Kit
![Benzene,1,1'-sulfonylbis[3,5-dibromo-4-(2,3-dibromopropoxy)-] (>85%)](https://cdn.genprice.uk/products/572/12047934/imageurl/trc-b290020-100mg.webp)