DHX9-IN-5
DHX9-IN-5 (compound 277) is a RNA helicase DHX9 inhibitor with an IC50 of 4.3 nM[1].
Product Specifications
CAS Number
[2973398-17-1]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhx9-in-5.html
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CN(C)C(C2=CC=C(N3CC4(C3)COC4)C=N2)=C1)NC5=CC(Cl)=CC(NS(=O)(C)=O)=C5
Molecular Formula
C23H24ClN5O4S
Molecular Weight
501.99
References & Citations
[1]Matthew H. Daniels, et al. Inhibitors of rna helicase dhx9 and uses thereof. WO2023154519A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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