DHX9-IN-4

DHX9-IN-4 (Compound 609) is an ATP-dependent inhibitor of RNA helicase A (DHX9) with potential for cancer research[1].

Product Specifications

CAS Number

[2973401-45-3]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dhx9-in-4.html

Purity

98.54

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC(C2=NC=C(C=N2)OC3CN(C3)C)=C(C)S1)NC4=CC(Cl)=CC(NS(=O)(C)=O)=C4

Molecular Formula

C21H22ClN5O4S2

Molecular Weight

508.01

References & Citations

[1]DANIELS Matthew H., et al. Preparation of imidazopyridines, thienopyrimidines, pyrrolopyrimidines and related heterocycles as inhibitors of RNA helicase DHX9 useful in treatment of cancers. World Intellectual Property Organization, WO2023154519 A1 2023-08-17