MAO-B-IN-27
MAO-B-IN-27 (Compound 12c) is a monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-27 has potent and selective MAO-B inhibitory effect for hMAO-B with an IC50 values of 8.9 nM. MAO-B-IN-27 can be used for the research of parkinson's disease (PD) [1].
Product Specifications
CAS Number
788824-83-9
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-b-in-27.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=CC=C(COC2=CC=C(CCN)C=C2)C=C1)F.Cl
Molecular Formula
C16H17ClF3NO
Molecular Weight
331.76
References & Citations
[1]Yeon SK, et al. Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy. Bioorg Med Chem. 2018 Jan 1;26 (1) :232-244.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15298099 1 Vial
Lentiviral mouse Trim54 shRNA (UAS) - Lentiviral mouse Trim54 shRNA (UAS, iRFP) plasmid
Sign In for Pricing
View Details 
