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DL-dithiothreitol-d10

DL-dithiothreitol-d10 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond[1][2].

Product Specifications

CAS Number

302912-05-6

Product Name Alternative

DTT-d10

UNSPSC

12352100

Hazard Statement

H302, H315, H319, H335

Target

Disulfidptosis; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Cancer

Purity

98.4

Solubility

10 mM in DMSO

Smiles

[2H]SC([2H])([2H])C(O[2H])([2H])C(O[2H])([2H])C([2H])([2H])S[2H]

Molecular Formula

C4D10O2S2

Molecular Weight

164.31

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24 (1) : 183.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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