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Des (benzylpyridyl) Atazanavir

Des (benzylpyridyl) Atazanavir (compound M1) is a N-dealkylation product of Atazanavir (HY-17367) metabolite. Atazanavir is a highly selective HIV-1 protease inhibitor. Des (benzylpyridyl) Atazanavir may contribute to the effectiveness Atazanavir but also to the toxicity and interactions. Des (benzylpyridyl) Atazanavir can be used for further research of Atazanavir effects[1].

Product Specifications

CAS Number

[1192224-24-0]

UNSPSC

12352005

Hazard Statement

H302

Target

Drug Metabolite; HIV; HIV Protease

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/des-benzylpyridyl-atazanavir.html

Solubility

10 mM in DMSO

Smiles

O[C@@H](CNNC([C@H](C(C)(C)C)NC(OC)=O)=O)[C@@H](NC([C@H](C(C)(C)C)NC(OC)=O)=O)CC1=CC=CC=C1

Molecular Formula

C26H43N5O7

Molecular Weight

537.65

Precautions

P264-P270-P330-P501

References & Citations

[1]R ter Heine, et al. Identification and profiling of circulating metabolites of atazanavir, a HIV protease inhibitor. Drug Metab Dispos. 2009 Sep;37 (9) :1826-40.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HIV-1

Available Sizes

Curated Selection

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